Online Mendelian Inheritance in Man (OMIM) (2024)

  1. Cunningham, J. T., Rodgers, J. T., Arlow, D. H., Vazquez, F., Mootha, V. K., Puigserver, P. mTOR controls mitochondrial oxidative function through a YY1-PGC-1-alpha transcriptional complex. Nature 450: 736-740, 2007. [PubMed: 18046414] [Full Text: https://doi.org/10.1038/nature06322]

  2. Donohoe, M. E., Zhang, L.-F., Xu, N., Shi, Y., Lee, J. T. Identification of a Ctcf cofactor, Yy1, for the X chromosome binary switch. Molec. Cell 25: 43-56, 2007. [PubMed: 17218270] [Full Text: https://doi.org/10.1016/j.molcel.2006.11.017]

  3. Flanagan, J. R., Becker, K. G., Ennist, D. L., Gleason, S. L., Driggers, P. H., Levi, B.-Z., Appella, E., Ozato, K. Cloning of a negative transcription factor that binds to the upstream conserved region of Moloney murine leukemia virus. Molec. Cell. Biol. 12: 38-44, 1992. [PubMed: 1309593] [Full Text: https://doi.org/10.1128/mcb.12.1.38-44.1992]

  4. Forlani, G., Giarda, E., Ala, U., Di c*nto, F., Salani, M., Tupler, R., Kilstrup-Nielsen, C., Landsberger, N. : The MeCP2/YY1 interaction regulates ANT1 expression at 4q35: novel hints for Rett syndrome pathogenesis. Hum. Molec. Genet. 19: 3114-3123, 2010. [PubMed: 20504995] [Full Text: https://doi.org/10.1093/hmg/ddq214]

  5. Gabriele, M., Vulto-van Silfhout, A. T., Germain, P.-L., Vitriolo, A., Kumar, R., Douglas, E., Haan, E., Kosaki, K., Takenouchi, T., Rauch, A., Steindl, K., Frengen, E., and 39 others. YY1 haploinsufficiency causes an intellectual disability syndrome featuring transcriptional and chromatin dysfunction. Am. J. Hum. Genet. 100: 907-925, 2017. [PubMed: 28575647] [Full Text: https://doi.org/10.1016/j.ajhg.2017.05.006]

  6. Gordon, S., Akopyan, G., Garban, H., Bonavida, B. Transcription factor YY1: structure, function, and therapeutic implications in cancer biology. Oncogene 25: 1125-1142, 2006. [PubMed: 16314846] [Full Text: https://doi.org/10.1038/sj.onc.1209080]

    See Also
    Transcription factor YY1: structure, function, and therapeutic implications in cancer biologyThe Role of Transcription Factor YY1 in the Biology of CancerYY1 interacts with guanine quadruplexes to regulate DNA looping and gene expressionNach rassistischem Gesang von Party-Gästen auf Sylt: Arbeitgeber kündigen Mitarbeitenden fristlos

  7. Hariharan, N., Kelley, D. E., Perry, R. P. Delta, a transcription factor that binds to downstream elements in several polymerase II promoters, is a functionally versatile zinc finger protein. Proc. Nat. Acad. Sci. 88: 9799-9803, 1991. [PubMed: 1946404] [Full Text: https://doi.org/10.1073/pnas.88.21.9799]

  8. Jeon, Y., Lee, J. T. YY1 tethers Xist RNA to the inactive X nucleation center. Cell 146: 119-133, 2011. [PubMed: 21729784] [Full Text: https://doi.org/10.1016/j.cell.2011.06.026]

  9. Kim, J., Kim, J. D. In vivo YY1 knockdown effects on genomic imprinting. Hum. Molec. Genet. 17: 391-401, 2008. [PubMed: 17977899] [Full Text: https://doi.org/10.1093/hmg/ddm316]

  10. Kim, J., Kollhoff, A., Bergmann, A., Stubbs, L. Methylation-sensitive binding of transcription factor YY1 to an insulator sequence within the paternally expressed imprinted gene, Peg3. Hum. Molec. Genet. 12: 233-245, 2003. [PubMed: 12554678] [Full Text: https://doi.org/10.1093/hmg/ddg028]

  11. Lee, M.-H., Lahusen, T., Wang, R.-H., Xiao, C., Xu, X., Hwang, Y.-S., He, W.-W., Shi, Y., Deng, C.-X. Yin Yang 1 positively regulates BRCA1 and inhibits mammary cancer formation. Oncogene 31: 116-127, 2012. [PubMed: 21666725] [Full Text: https://doi.org/10.1038/onc.2011.217]

  12. Liu, H., Schmidt-Supprian, M., Shi, Y., Hobeika, E., Barteneva, N., Jumaa, H., Pelanda, R., Reth, M., Skok, J., Rajewsky, K., Shi, Y. Yin Yang 1 is a critical regulator of B-cell development. Genes Dev. 21: 1179-1189, 2007. [PubMed: 17504937] [Full Text: https://doi.org/10.1101/gad.1529307]

    See Also
    YY1 is an initiator sequence-binding protein that directs and activates transcription in vitro

  13. Oei, S. L., Shi, Y. Transcription factor Yin Yang 1 stimulates poly(ADP-ribosyl)ation and DNA repair. Biochem. Biophys. Res. Commun. 284: 450-454, 2001. [PubMed: 11394900] [Full Text: https://doi.org/10.1006/bbrc.2001.4985]

  14. Park, K., Atchison, M. L. Isolation of a candidate repressor/activator, NF-E1 (YY-1, delta), that binds to the immunoglobulin kappa 3-prime enhancer and the immunoglobulin heavy-chain micro-E1 site.. Proc. Nat. Acad. Sci. 88: 9804-9808, 1991. [PubMed: 1946405] [Full Text: https://doi.org/10.1073/pnas.88.21.9804]

  15. Santiago, F. S., Ishii, H., Shafi, S., Khurana, R., Kanellakis, P., Bhindi, R., Ramirez, M. J., Bobik, A., Martin, J. F., Chesterman, C. N., Zachary, I. C., Khachigian, L. M. Yin Yang-1 inhibits vascular smooth muscle cell growth and intimal thickening by repressing p21(WAF1/Cip1) transcription and p21(WAF1/Cip1)-Cdk4-cyclin D1 assembly. Circ. Res. 101: 146-155, 2007. [PubMed: 17556661] [Full Text: https://doi.org/10.1161/CIRCRESAHA.106.145235]

  16. Shi, Y., Seto, E., Chang, L.-S., Shenk, T. Transcriptional repression by YY1, a human GLI-Kruppel-related protein, and relief of repression by adenovirus E1A protein. Cell 67: 377-388, 1991. [PubMed: 1655281] [Full Text: https://doi.org/10.1016/0092-8674(91)90189-6]

  17. Sigova, A. A., Abraham, B. J., Ji, X., Molinie, B., Hannett, N. M., Guo, Y. E., Jangi, M., Giallourakis, C. C., Sharp, P. A., Young, R. A. Transcription factor trapping by RNA in gene regulatory elements. Science 350: 978-981, 2015. [PubMed: 26516199] [Full Text: https://doi.org/10.1126/science.aad3346]

  18. Sui, G., Affar, E. B., Shi, Y., Brignone, C., Wall, N. R., Yin, P., Donohoe, M., Luke, M. P., Calvo, D., Grossman, S. R., Shi, Y. Yin Yang 1 is a negative regulator of p53. Cell 117: 859-872, 2004. [PubMed: 15210108] [Full Text: https://doi.org/10.1016/j.cell.2004.06.004]

  19. Vissers, L. E. L. M., de Ligt, J., Gilissen, C., Janssen, I., Steehouwer, M., de Vries, P., van Lier, B., Arts, P., Wieskamp, N., del Rosario, M., van Bon, B. W. M., Hoischen, A., de Vries, B. B. A., Brunner, H. G., Veltman, J. A. A de novo paradigm for mental retardation. Nature Genet. 42: 1109-1112, 2010. [PubMed: 21076407] [Full Text: https://doi.org/10.1038/ng.712]

  20. Yan, B., Heus, J., Lu, N., Nichols, R. C., Raben, N., Plotz, P. H. Transcriptional regulation of the human acid alpha-glucosidase gene: identification of a repressor element and its transcription factors Hes-1 and YY1. J. Biol. Chem. 276: 1789-1793, 2001. [PubMed: 11038350] [Full Text: https://doi.org/10.1074/jbc.M005959200]

  21. Yan, B., Raben, N., Plotz, P. H. Hes-1, a known transcriptional repressor, acts as a transcriptional activator for the human acid alpha-glucosidase gene in human fibroblast cells. Biochem. Biophys. Res. Commun. 291: 582-587, 2002. [PubMed: 11855828] [Full Text: https://doi.org/10.1006/bbrc.2002.6483]

  22. Yao, Y.-L., Dupont, B. R., Ghosh, S., Fang, Y., Leach, R. J., Seto, E. Cloning, chromosomal localization and promoter analysis of the human transcription factor YY1. Nucleic Acids Res. 26: 3776-3783, 1998. [PubMed: 9685495] [Full Text: https://doi.org/10.1093/nar/26.16.3776]

  23. Zhou, X., Xian, W., Zhang, J., Zhu, Y., Shao, X., Han, Y., Qi, Y., Ding, X., Wang, X. YY1 binds to the E3-prime enhancer and inhibits the expression of the immunoglobulin kappa gene via epigenetic modifications. Immunology 155: 491-498, 2018. [PubMed: 30098214] [Full Text: https://doi.org/10.1111/imm.12990]

  24. Zhu, W., Lossie, A. C., Camper, S. A., Gumucio, D. L. Chromosomal localization of the transcription factor YY1 in the mouse and human. Mammalian Genome 5: 234-236, 1994. [PubMed: 7912122] [Full Text: https://doi.org/10.1007/BF00360552]

Online Mendelian Inheritance in Man (OMIM) (2024)
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